24 Temmuz 2008 Perşembe

Dynamic HTML Weekend Crash Course

Book DescriptionFifteen hours. With this book, that's all it takes for a Web designer to master the fundamentals of Dynamic HTML -- and start embellishing Web pages with animations, pop-up menus, rollovers, and more. The book presumes some knowledge of HTML, but no knowledge of the other chief components of DHTML, Cascading Style Sheets and JavaScript, which both receive detailed coverage. The CD-ROM has source code, Web development tools, and more. Book InfoFifteen hours.

With this book, that's all it takes for a Web designer to master the fundamentals of Dynamic HTML, and start embellishing Web pages with animations, pop-up menus, rollovers, and more. Softcover. CD-ROM included

Product Details
Paperback: 387 pages
Publisher: Hungry Minds; Pap/Cdr edition (November 15, 2001)
Language: English
ISBN-10: 0764548905
ISBN-13: 978-0764548901
Product Dimensions: 9.2 x 7.4 x 0.9 inches


The Art and Science of CSS

Product DescriptionCSS-based design doesn't need to be boring. The Art & Science of CSS brings together a talented collection of designers who will show you how to take the building blocks of your web site's design (such as headings, navigation, forms, and more) and bring them to life with fully standards-compliant CSS.
This full color book helps you to design web sites that not only work well across all browsers, are easy to maintain, and are highly accessible, but are also visually stunning.
Create truly attention-grabbing headings.
Discover multiple ways to present images effectively.
Use background images to give your site zest.
Build usable and attractive navigation.
Design forms that are stylish and functional.
Learn how to break away from the square box gclich.
Create funky tables.
And lots moreFrom the Publisher
Jonathan Snook, Steve Smith, Jina Bolton, Cameron Adams, and David Johnson, five of the biggest names in CSS design have joined forces to bring you The Art & Science Of CSS. Beautifully presented in full color, this book will teach you how to apply innovative CSS-based techniques to create visually stunning headings, forms, menus, navigation, backgrounds, and much more... Using The Art & Science Of CSS, you'll see just how easy it is to unleash your creative talents and design inspirational web sites with CSS. All designs in this book are visually appealing and inspiring. The CSS code used to create each of the components is included and guaranteed to be simple, efficient and cross-browser compatible. Among its many treasures, this book will show you how to:
Format calendars, menus and table of contents using CSS
Create horizontal, vertical and tab-based navigation systems using CSS
Create rounded corners using CSS
Design stylish Website headings
Put together funky & artistic Website backgrounds
Use CSS to render blockquotes, dates and lists in a visually appealing manner All designs in this book are visually appealing and inspiring. The code CSS code used to create each of the components is provided and is guaranteed to be simple, efficient and cross-browser compatible.Who Should Read This Book?
This book is ideal for anyone who wants to gain the practical skills involved in using CSS to make attractive web sites, especially if you're not the type who likes to learn by memorizing a formal specification and then trying to work out which browsers implemented it completely (does anyone enjoy reading specifications?). The only knowledge you'll need to have is some familiarity with HTML.

This book will give designers the skills they need to implement their ideas, and provides developers with creative inspiration through practical examples.About the AuthorCameron Adams has been adding to the Internet for over seven years and now runs his own design and development business: www.themaininblue.com. He likes to combine the aesthetic with the technological on his Weblog, which contains equal parts of JavaScript, design and CSS.Jina Bolton, Interactive Designer, holds a Bachelor of Fine Arts degree in Computer Arts and Graphic Design fom Memphis College of Art. In addition to being featured in CSS Professional Style and Web Designing magazine, Jina consults for variuos agencies and organizations including the World Wide Web Consortium.

She enjoys traveling, is learning Italian, and considers herself a shushi-enthusiast.David Johnson is one of those evil .NET developers from Melbourne, Australia. He is the senior developer at Lemonade (http://www.lemonade.com.au), and his role includes C# programming, database design using SQL Server, and front-end development using XHTML and CSS. He makes up for his evil deeds by being a firm believer in web standards and accessibility, and forcing .NET to abide by these rules. His favorite candy is Sherbies.

Steve Smith is the lead Web developer with the University of Notre Dame Web Group, and believes in "finding joy in small steps" when it comes to advocating web standards.Jonathan Snook has been involved in the web since '95, and is lucky to be able to call his hobby a career. He worked in wb agencies for over six years and has worked with high profile clients in government, the private sector, and non-profit organizations. Jonathan Snook currently runs his own web development business from Ottawa, Canada and continues to write about what he loves on his blog at Snook.ca.

Product Details
Paperback: 224 pages
Publisher: SitePoint; 1 edition (March 9, 2007)
Language: English
ISBN-10: 0975841971
ISBN-13: 978-0975841976
Product Dimensions: 9.9 x 8 x 0.6 inches


Foundations of Microsoft Expression Web: The Basics and Beyond

Product Description
Microsoft Expression Suite promises new levels of power in creating rich dynamic user experiences on the web; Expression Web, one of the excellent programs within the suite, is a powerful web site creation tool that allows you to rapidly build up standards-compliant web pages, style them with CSS, add dynamic ASP.NET functionality to them, and publish them to the weball from the comfort of one program.
Foundations of Microsoft Expression Web: The Basics and Beyond is one of the first books available on the program. The authorexpert MS trainer and MVP Cheryl D. Wisestarts with the very basics, and then takes you to an advanced level through a series of practical real-world exercises. No prior knowledge of Microsoft Expression Suite is assumed, and the book is written with a highly professional tone. This makes it extremely useful whether youre a beginner or an advanced web developer or designer who wants to make use of the software.About the AuthorCheryl D. Wise, founder and director of WiserWays LLC, has been creating web sites since 1994.

A member of the Guild of Accessible Web Designers and a Certified Professional Web Developer (World Organization of Webmasters), Cheryl first received the Most Valuable Professional Award from Microsoft for FrontPage in 2003 and has received the award every year since. She has been teaching others to create standards-complaint accessible web sites at Start to Web, and has been doing other online training since 2004.

Product Details
Paperback: 392 pages
Publisher: Apress (May 7, 2007)
Language: English
ISBN-10: 1590598059
ISBN-13: 978-1590598054
Product Dimensions: 9.2 x 7 x 1.2 inches


Commercializing Micro-Nanotechnology Products

Editorial Reviews
Product DescriptionMicro-nanotechnologies (MNT) are already making a profound impact on our daily lives. New applications are well underway in the US, Asia, and Europe. However, their potentially disruptive nature, along with the publics concerns, has produced a number of challenges. Commercializing Micro-Nanotechnology Products provides a snapshot of the current market situation and details the need for MNT development. It outlines the problems facing todays businesses and discusses the processes for commercialization, road mapping, technology transfer analysis, and entrepreneurial development.
The book begins by detailing the steps required to turn an idea into a marketable product. The editors give examples of previously successful products and relate to their own experiences in development. Next, the text focuses on the importance of entrepreneurship and the required steps to finance and develop a marketing strategy. It contains various definitions of nanotechnology and how each relates to roadmap and production issues.
Three detailed case studies from the leading MNT development and manufacturing companies describe how each venture started and progressed to become a market leader. These studies offer valuable insight into overcoming the challenges related to achieving financial backing and specifying the right product for development.

This reference provides the only insightful appraisal of the current status of micro-nanotechnology products. It describes a concise process for product commercialization, from market research to end product realization. Commercializing Micro-Nanotechnologies provides a clear strategy for choosing the right product to development and overcoming challenges in the growing global market.

Product Details
Hardcover: 288 pages
Publisher: CRC (November 19, 2007)
Language: English
ISBN-10: 0849383153
ISBN-13: 978-0849383151
Product Dimensions: 9.2 x 6.2 x 0.8 inches



Mathematical Methods for Knowledge Discovery and Data Mining

Product DescriptionThe field of data mining has seen a demand in recent years for the development of ideas and results in an integrated structure. Mathematical Methods for Knowledge Discovery & Data Mining focuses on the mathematical models and methods that support most data mining applications and solution techniques, covering such topics as association rules; Bayesian methods; data visualization; kernel methods; neural networks; text, speech, and image recognition; and many others.

This Premier Reference Source is an invaluable resource for scholars and practitioners in the fields of biomedicine, engineering, finance and insurance, manufacturing, marketing, performance measurement, and telecommunications

Product Details
Hardcover: 371 pages
Publisher: Idea Group Reference (October 4, 2007)
Language: English
ISBN-10: 1599045281
ISBN-13: 978-1599045283
Product Dimensions: 11.1 x 8.6 x 1.1 inches



Supersymmetry in Particle Physics: An Elementary Introduction

Review"If you are a physics student with good knowledge of quantum field theory or an experimentalist working on high-energy physics, and need a quick reference on supersymmetry (SUSY) on which you can find the rationale behind it, in addition to the most useful cross-section formulae, then the book by Ian Aitchison is probably the best choice for you. If you have no idea about SUSY but want (or need) to learn its basics, again this is a very good choice. " Diego Casadei NYU and CERN Product DescriptionSupersymmetry represents the culmination of the search for fundamental symmetries that has dominated particle physics for 50 years.
Traditionally, the constituents of matter (fermions) were regarded as different from the particles (bosons) transmitting the forces between them. In supersymmetry, fermions and bosons are unified. Intended for graduate students in particle physics, and researchers in experimental and phenomenological supersymmetry, this is the first textbook to provide a simple introduction to a previously formidably technical field. Its elementary, practical treatment brings readers to the frontier of contemporary research, in particular the experiments at the Large Hadron Collider.

Theories are constructed through an intuitive 'trial and error' approach. Basic elements of spinor formalism and superfields are introduced, allowing readers to access more advanced treatments. Emphasis is placed on physical understanding, and on detailed derivations of important steps. Many short exercises are included, making for a valuable and accessible self-study tool.

Product Details
Hardcover: 236 pages
Publisher: Cambridge University Press; 1 edition (October 22, 2007)
Language: English
ISBN-10: 0521880238
ISBN-13: 978-0521880237
Product Dimensions: 9.8 x 6.9 x 0.7 inches



Nanoscale Science and Technology

Editorial Reviews
Review"…a refreshing work, a very readable introduction to nanotechnology…" (CHOICE, February 2006 )
“ …the book reads well (and) abounds with instructive diagrams …” (Chemistry World, July 2005) Product DescriptionNanotechnology is a vital new area of research and development addressing the control, modification and fabrication of materials, structures and devices with nanometre precision and the synthesis of such structures into systems of micro- and macroscopic dimensions. Future applications of nanoscale science and technology include motors smaller than the diameter of a human hair and single-celled organisms programmed to fabricate materials with nanometer precision.Miniaturisation has revolutionised the semiconductor industry by making possible inexpensive integrated electronic circuits comprised of devices and wires with sub-micrometer dimensions.

These integrated circuits are now ubiquitous, controlling everything from cars to toasters. The next level of miniaturisation, beyond sub-micrometer dimensions into nanoscale dimensions (invisible to the unaided human eye) is a booming area of research and development. This is a very hot area of research with large amounts of venture capital and government funding being invested worldwide, as such Nanoscale Science and Technology has a broad appeal based upon an interdisciplinary approach, covering aspects of physics, chemistry, biology, materials science and electronic engineering.

Kelsall et al present a coherent approach to nanoscale sciences, which will be invaluable to graduate level students and researchers and practising engineers and product designers

Product Details
Hardcover: 472 pages
Publisher: Wiley (April 29, 2005)
Language: English
ISBN-10: 0470850868
ISBN-13: 978-0470850862
Product Dimensions: 9.7 x 6.8 x 1.4 inches



Joint Structure And Function: A Comprehensive Analysis

Editorial Reviews
Product DescriptionStriking an optimum user-friendly balance between basic and more advanced content, Joint Structure and Function is the ideal text for your program's "Introduction to Kinesiology" course. It is targeted primarily for physical therapy students (but also can be used by occupational therapy and athletic training students) who are preparing for entry-level practice involved in the assessment of and intervention in human musculoskeletal function and dysfunction. Well-referenced, up-to-date research and the liberal use of figures, examples, and tables make this the most educationally comprehendible text on the market. Book InfoOhio University, Athens. Updated and expanded edition of a text for physical therapy students on human musculoskeletal function and dysfunction, emphasizing the joints. Includes new information and theories in muscle physiology, tissue composition, and the application of normal and abnormal force.

Product Details
Hardcover: 588 pages
Publisher: F. A. Davis Company; 4 edition (June 30, 2005)
Language: English
ISBN-10: 0803611919
ISBN-13: 978-0803611917
Product Dimensions: 11 x 8.4 x 1.3 inches



Advanced Transport Phenomena: Fluid Mechanics and Convective Transport Processes

Review'Advanced transport phenomena contains a detailed discussion of modern analytic methods for the solution of fluid mechanics, ... With a focus on solving representative problems, the author aims to teach students to think about the solution of transport problems.' The Chemical Engineer Product DescriptionAdvanced Transport Phenomena is ideal as a graduate textbook. It contains a detailed discussion of modern analytic methods for the solution of fluid mechanics, and heat and mass transfer problems, focusing on approximations based upon scaling and asymptotic methods, beginning with the derivation of basic equations and boundary conditions and concluding with linear stability theory. Also covered are unidirectional flows, lubrication and thin-film theory, creeping flows, boundary layer theory, and convective heat and mass transport at high and low Reynolds numbers. The emphasis is on basic physics, scaling and non-dimensionalization, and approximations that can be used to obtain solutions due either to geometric simplifications, or large or small values of dimensionless parameters.
The author emphasizes setting up problems and extracting as much information as possible short of obtaining detailed solutions of differential equations. The book is also focused on the solutions of representative problems. This reflects the author's bias toward learning to think about the solution of transport problems

Product Details
Hardcover: 932 pages
Publisher: Cambridge University Press; 1 edition (June 18, 2007)
Language: English
ISBN-10: 0521849101
ISBN-13: 978-0521849104
Product Dimensions: 10.1 x 7 x 1.9 inches


Linux Desktop Hacks: Tips & Tools for Customizing and Optimizing your OS

Editorial Reviews
Product DescriptionThe KDE and Gnome desktops have developed into mature operating environments. These technologies not only act as interfaces between the user, the powerful Linux kernel and GNU operating system, but they do so in a fun and intuitive way. Many users are content with the tools and facilities included with these desktops, but--for those who are ready to probe a little deeper--much more functionality can be found by going under the hood. With hacks that any user can follow, Linux Desktop Hacks demonstrates how easy it is to modify Linux to suit your desires. The book is packed with tips on customizing and improving the interface, boosting performance, administering your desktop, and generally making the most out of what X, KDE, Gnome, and the console have to offer. From the practical to the whimsical, and some things you never thought of trying, the hacks in the book include the following, and more:

Kill and Resurrect the Master Boot Record
Jazz Up Your Debian System Boot
Energize Your Console with Macro Music Magic
Konquer Remote Systems Without Passwords
Run KDE on the Bleeding Edge
View Microsoft Word Documents in a Terminal
Read Yahoo! Mail from Any Email Client
Motion Capture and Video Conferencing Fun
Automate Your Life with cron
Protect Yourself from Windows Applications
Make an Internet Connection Using Bluetooth and a Mobile Phone
Print to Unsupported Printers

Accelerate Your GamingIf you're yearning for information to make the Linux desktop easier, more powerful, and more fun, Linux Desktop Hacks is just the ticket. About the AuthorNicholas Petreley began his career in computing in 1983 as an Assembly-language programmer for a signal-processing research and development firm called Adaptronics, located in McLean, Virginia, and he hasn't been able to escape the field since. After getting a taste of writing as a weekly columnist for the Times in New Jersey, Nick began spending more time with the English language than with Pascal, C, C++, and the dozens of other languages that previously dominated his life. Nick's former lives also include conference advisor for LinuxWorld Expo, creator of the Golden Penguin Bowl quiz show, editorial director of LinuxWorld, editor-in-chief of Network Computing World, executive editor of the InfoWorld Test Center, award-winning columnist for InfoWorld, and regular technical columnist for ComputerWorld. You can find his current articles on Newsforge and in other publications under various pseudonyms. He is a columnist for Tux magazine, the author of the Official Fedora Companion, a part-time Evans data analyst, a freelance writer, a creator and maintainer of the VAR-oriented web site (http://www.varlinux.org), and a professional open source consultant.
Jono Bacon is an established writer, developer, and musician. Jono has been working as a full-time writer and technology consultant/developer since 2000, for a variety of publishers and companies. They include Linux Format, Linux Pro, Linux Magazine, Linux User & Developer, Linux Journal, PC Plus, MacFormat, MacTech, Digital Home, Newsforge, Sitepoint, and ContentPeople. Jono has also worked as a writer/consultant/developer for Trolltech, Apple, theKompany.com, the University of Wolverhampton, Delta Institute, and others. In addition to this work, Jono has been a part of the Linux community since 1998 and has worked for various free software projects including KDE and Kafka, and he founded Linux UK, the KDE Usability Study, KDE::Enterprise, and the Infopoint Project. He currently works on various free software projects, as well as for OpenAdvantage in Birmingham, UK, as a professional open source consultant.

Product Details
Paperback: 342 pages
Publisher: O'Reilly Media, Inc. (March 28, 2005)
Language: English
ISBN-10: 0596009119
ISBN-13: 978-0596009113
Product Dimensions: 8.9 x 6 x 0.9 inches


Use Case Driven Object Modeling with UMLTheory and Practice

Product Details
Hardcover: 472 pages
Publisher: Apress (January 22, 2007)
Language: English
ISBN-10: 1590597745
ISBN-13: 978-1590597743
Product Dimensions: 9.2 x 6.1 x 0.8 inches

Firefox Secrets: A Need-To-Know Guide

Product Details
Paperback: 292 pages
Publisher: SitePoint; Pap/Cdr edition (June 15, 2005)
Language: English
ISBN-10: 0975240242
ISBN-13: 978-0975240243
Product Dimensions: 9 x 7.1 x 0.8 inches

Handbook of Physics

Product Details
Hardcover: 1248 pages
Publisher: Springer; 1st ed. 2002. Corr. 2nd printing edition (January 13, 2006)
Language: English
ISBN-10: 0387952691
ISBN-13: 978-0387952697
Product Dimensions: 9.1 x 6.2 x 1.4 inches

23 Temmuz 2008 Çarşamba

Linear Programming: Foundations and Extensions

Product Details
Hardcover: 464 pages
Publisher: Springer; 3rd ed. edition (November 26, 2007)
Language: English
ISBN-10: 0387743871
ISBN-13: 978-0387743875
Product Dimensions: 9.2 x 6.3 x 1.3 inches

Sequence Data Mining (Advances in Database Systems)

Product Details
Hardcover: 152 pages
Publisher: Springer; 1 edition (August 9, 2007)
Language: English
ISBN-10: 0387699368
ISBN-13: 978-0387699363
Product Dimensions: 9.3 x 6.2 x 0.6 inches

Optical Properties Of Surfaces

By Dick Bedeaux, Jan Vlieger
Publisher: Imperial College Press
Number Of Pages: 464
Publication Date: 2004-07-31


Cold Spray Technology

Product Details
Format: Kindle Edition
Print Length: 336 pages
Publisher: Elsevier Science; 1 edition (November 13, 2006)
Sold by: Amazon Digital Services

Tandem Techniques (Separation Science Series)

A comprehensive manual for the analyst (or chromatographer) for evaluating and using the various tandem systems obtained by combining different methods of chromatography and spectroscopy. It introduces the reader to the different separation techniques that can be combined with spectroscopic techniques. Gives essential details of the different interface designs that are necessary for each tandem technique. Provides practical examples of the use of each technique, describing the analytical performance and sensitivity in terms that allow direct comparison between techniques. In addition to describing research prototype tandem combinations, it presents commercially available systems. Offers many detailed diagrams to facilitate rapid comprehension

By Raymond P. W. Scott
Publisher: Wiley
Number Of Pages: 538
Publication Date: 1997-03


The Poison Paradox: Chemicals As Friends and Foes

Product Details
Publisher: Oxford University Press, USA (2005)

World Development: An Introduction

Prodromos Panayiotopoulos, World Development: An Introduction

Pluto Press ISBN 0745314074 2001 PDF 2.96 MB 311 pages

Do the structures of the world economy invariably work against theinterests of the Third World? What is the impact of industrialization? How does it affect people and their livelihoods, gender relations, theenvironment, movements for social justice and democracy?World Development offers answers to these questions. A comprehensive introductory guide for students, teachers, volunteers and NGO workers in development, World Development examines the substantive issues surrounding development, industrialization and globalization and places them within a historic context


Excellence in Communicating Organizational Strategy

Product Details
Paperback: 261 pages
Publisher: State University of New York Press (July 2001)
Language: English
ISBN-10: 0791450341
ISBN-13: 978-0791450345
Product Dimensions: 9 x 5.9 x 0.6 inches

Data-driven Block Ciphers for Fast Telecommunication Systems

Product Details
Hardcover: 208 pages
Publisher: AUERBACH (December 14, 2007)
Language: English
ISBN-10: 1420054112
ISBN-13: 978-1420054118
Product Dimensions: 9.3 x 6.2 x 0.7 inches

The Splendid Feast of Reason

Product Details
Paperback: 265 pages
Publisher: University of California Press; 1 edition (May 5, 2003)
Language: English
ISBN-10: 0520239113
ISBN-13: 978-0520239111
Product Dimensions: 7.9 x 5.3 x 0.7 inches

Content Syndication with RSS

Product Details
Paperback: 256 pages
Publisher: O'Reilly; 1st edition (April 1, 2003)
Language: English
ISBN-10: 0596003838
ISBN-13: 978-0596003838
Product Dimensions: 9.3 x 7.1 x 0.5 inches

Characterization of Materials, 2 Volume Set

Product Details
Hardcover: 1392 pages
Publisher: Wiley-Interscience (February 7, 2003)
Language: English
ISBN-10: 0471268828
ISBN-13: 978-0471268826
Product Dimensions: 11.3 x 8.7 x 3 inches

Poultry Genetics, Breeding and Biotechnology

Hardcover: 720 pages
Publisher: CABI; 1 edition (September 4, 2003)
Language: English
ISBN-10: 0851996604
ISBN-13: 978-0851996608
Product Dimensions: 9.7 x 7.2 x 2 inches

Academia to Biotechnology: Career Changes at any Stage

Product Details
Paperback: 186 pages
Publisher: Academic Press; 1 edition (September 15, 2004)
Language: English
ISBN-10: 0122841514
ISBN-13: 978-0122841514
Product Dimensions: 8.8 x 5.9 x 0.5 inches

Polymer Chemistry: A Practical Approach

Publisher: Oxford University Press, USA
Number Of Pages: 266
Publication Date: 2004-11-12
Sales Rank: 1299831
tISBN / ASIN: 0198503091
EAN: 9780198503095
Binding: Hardcover
Manufacturer: Oxford University Press, USA
Studio: Oxford University Press, USA



Mechanical Behavior of Materials

Product DescriptionThis textbook is for courses on Mechanical Behavior of Materials taught in departments of Mechanical Engineering and Materials Science. The text includes numerous examples and problems for student practice. The book emphasizes quantitative problem solving. End of the chapter notes are included to increase students' interest. This text differs from others because the treatment of plasticity has greater emphasis on the interrelationship of the flow, effective strain and effective stress and their use in conjunction with yield criteria to solve problems. The treatment of defects is new. Schmid's law is generalized for complex stress states. Its use with strains allows for prediction of R-values for textures. Another feature is the treatment of lattice rotations and how they lead to deformation textures. The chapter on fracture mechanics includes coverage of Gurney's approach. Much of the analysis of particulate composites is new. Few texts include anything on metal forming. Book DescriptionThis text for courses on Mechanical Behavior of Materials in Mechanical Engineering and Materials Science, includes numerous examples and problems and emphasizes quantitative problem solving. It considers numerous topics including mechanical testing to determine material properties, plasticity for FEM analyses, means of altering mechanical properties and several modes of failure.

Product Details
Hardcover: 446 pages
Publisher: Cambridge University Press (May 2, 2005)
Language: English
ISBN-10: 0521846706
ISBN-13: 978-0521846707
Product Dimensions: 10 x 7.1 x 1.2 inches



Data Monitoring in Clinical Trials

"This book is a must-read for individuals serving on or supporting data monitoring committees as well as statisticians and other disciplines involved in the design and analysis of clinical trials with interim monitoring." Journal of Biopharmaceutical Sciences, Issue 6, 2006
"This edited book gives a brief introduction to data-monitoring committees for clinical trials  . It has been my experience that many persons asked to serve on data-monitoring committees have scientific or clinical expertise relevant to the trial, but have little or no understanding of the purpose of the data-monitoring committee  . Such individuals would greatly benefit from reading this book prior to serving on a data-monitoring committee, as would anyone wishing to gain some insight into the responsibilities and challenges facing data-monitoring committees." (S. W. Lagakos, Short Book Reviews, Vol. 26 (1), 2006)
"The chapters are clearly written, and the take-home lessons are apparent. The 70 contributing authors represent a full range of perspectives on data monitoring and give balanace to the exposition. ...In summary, the book achieves its goal and deserves a place in every medical school's library." (J. Wade Davis, Journal of the American Statistical Association, Vol. 102, No. 477, 2007)
"This book is highly recommended for anyone who starts to serve on a DMC or is already a member of such a board, and also for people in academia, industry, and regulatory agencies as well as for students in biostatistics, epidemiology, clinical trails, and medical ethics." Iris Pigeot, Biometrics, December 2006)
"This book illustrates the complexity of data monitoring processes through a series of case studies presented by many distinguished clinical trial experts.  A total of 29 case studies have been discussed.  This book would be quite useful for the researchers, investigators and individuals serving on the DMC, or planning to do so, who would like to understand the application of data monitoring principles in clinical trials. I have thoroughly enjoyed reading this book and I think it has served its purpose 

Product Description

Randomized clinical trials are the gold standard for establishing many clinical practice guidelines and are central to evidence based medicine. Obtaining the best evidence through clinical trials must be done within the boundaries of rigorous science and ethical principles. One fundamental principle is that trials should not continue longer than necessary to reach their objectives. Therefore, trials must be monitored for recruitment progress, quality of data, adherence to patient care or prevention standards, and early evidence of benefit or harm. Frequently, a group of external experts, independent from the investigators and trial sponsor, is charged with this monitoring responsibility, especially for safety and early benefit. This group is referred to by various names, such as a data monitoring committee or a data and safety monitoring board. This book, through a series of case studies presented by many distinguished clinical trial experts, illustrates the complexity of this monitoring process. The editors provide an overview of the process and a summary of a multitude of the lessons learned from the cases presented.
This book should be useful to anyone serving on a data and safety monitoring board, or planning to do so, for colleagues in academia, industry and governmental agencies, and for teaching students in biostatistics, epidemiology, clinical trials and medical ethics. No other text has as extensive a collection of cases which provide insight into the many issues, often conflicting, that must be examined before recommendations to continue or discontinue a trial can be made. While depth in statistical methods is not required, some familiarity with statistical design and analysis issues in clinical trials is helpful. The cases cover trials which were terminated early for convincing evidence of benefit, or for harmful effects. Cases with complex issues are also included. This series of cases should provide broad background information for potential monitoring committee members and better prepare them for the challenges that may exist in the trials for which they are responsible.
The three editors have contributed two overview chapters as well as several case studies to go along with cases contributed by a distinguished group of colleagues experienced in the design, monitoring and analysis of clinical trials. Dr. David DeMets is currently Professor and Chair, Department of Biostatistics and Medical Informatics at the University of Wisconsin-Madison. He is past president of the Eastern North American Region (ENAR) of the International Biometric Society, a past member of the Board of Directors of the American Statistical Association and an elected Fellow. He recently received the Robert Gordon Lectureship Award, given by the National Institutes of Health, for significant contributions to the field of clinical trials. Dr. Curt Furberg, is currently Professor (and former Chair) of the Department of Public Health Sciences at Wake Forest University. Previously, he was Head of the Clinical Trials Branch and Associate Director of the Clinical Applications and Prevention Program at the National Heart, Lung, and Blood Institute. Dr. Lawrence Friedman is a former Director of the Division of Epidemiology and Clinical Applications and a former Assistant Director for Ethics and Clinical Research at the National Heart, Lung, and Blood Institute. All three are past presidents of the Society of Clinical Trials. The editors have collaborated previously as coauthors of a text: the Fundamentals of Clinical Trials.

Product Details
Paperback: 374 pages
Publisher: Springer; 1 edition (September 30, 2005)
Language: English
ISBN-10: 0387203303
ISBN-13: 978-0387203300
Product Dimensions: 9.1 x 6 x 0.8 inches